Dobutamine Impurity 20 HCl CAS 140165-60-2 (free base)
| CAS No. | 140165-60-2 (free base) |
| Molecular Formula | C20H27NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dobutamine Impurity 20 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Dobutamine Impurity 20 HCl (CAS 140165-60-2 (free base)), a pharmacopoeial impurity reference standard (molecular formula C20H27NO3HCl, MW 365.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Dobutamine Impurity 20 HCl (C20H27NO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H27NO3 HCl |
| Molecular Weight | 365.90 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dobutamine Standards
- Dobutamine Impurity 4 (CAS 104-20-1)
- Dobutamine Impurity 52 (CAS 1059182-81-8)
- Dobutamine Impurity 48 (CAS 1165-58-8)
- Dobutamine Impurity 7 (CAS 126521-63-9)
- Dobutamine Impurity 8 (CAS 14165-67-4)
- Dobutamine Impurity N1 (CAS 19713-28-1)
- Dobutamine Impurity 26 (CAS 243139-71-1)
- Dobutamine Impurity 23 (CAS 2514709-72-7)
Recommended Standards
- (2`R,2S,cis)-Saxagliptin (CAS 1564265-93-5)
- Ilaprazole Impurity 15 (CAS CATO-C4X-113015)
- Lamivudine EP impurity A (CAS 173602-25-0)
- 1-(Benzylsulfonyl)piperidin-4-amine (CAS 209917-52-2)
- (Z)-Buta-1,3-diene-1-sulfonamide (CAS 83170-38-1)
- 4-(ethoxy(phenyl)methyl)-1,1'-biphenyl (CAS 2137934-65-5)
- Potassium 4-methylbenzoate (CAS 16518-25-5)
- 2-(2-Amino-1-methyl-1H-imidazol-4-yl)-2-oxoacetic acid (CAS 758642-20-5)
- 4-(2-Aminoethyl)-5-(tert-butyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 878208-77-6)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
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